HCSGD entry for ASIC3

1. General information

Official gene symbolASIC3
Entrez ID9311
Gene full nameacid-sensing (proton-gated) ion channel 3
Other gene symbolsACCN3 DRASIC SLNAC1 TNaC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001101Response to acidIEAbiological_process
GO:0005261Cation channel activityTASmolecular_function
GO:0005272Sodium channel activityIEA TASmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006810TransportTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007600Sensory perceptionTASbiological_process
GO:0009408Response to heatIEAbiological_process
GO:0015280Ligand-gated sodium channel activityIEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030165PDZ domain bindingIEAmolecular_function
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0042931Enterobactin transporter activityIEAmolecular_function
GO:0050965Detection of temperature stimulus involved in sensory perception of painIEAbiological_process
GO:0050966Detection of mechanical stimulus involved in sensory perception of painIEAbiological_process
GO:0050968Detection of chemical stimulus involved in sensory perception of painIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08395223590.99401775390.60990467801.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.4985630624
GSE28863_A2Down-0.0889093119
GSE28863_A3Down-0.0359172783
GSE28863_A4Up0.1216738968
GSE48662Up0.5762155679

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AgmatineDB08838 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.