HCSGD entry for MARS2
1. General information
| Official gene symbol | MARS2 |
|---|---|
| Entrez ID | 92935 |
| Gene full name | methionyl-tRNA synthetase 2, mitochondrial |
| Other gene symbols | MetRS mtMetRS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004825 | Methionine-tRNA ligase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005759 | Mitochondrial matrix | IDA TAS | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006431 | Methionyl-tRNA aminoacylation | IDA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0049808062 | 0.1091552487 | 0.1851692090 | 0.6318617330 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0094086634 |
| GSE13712_SHEAR | Down | -0.0708761891 |
| GSE13712_STATIC | Down | -0.3671284182 |
| GSE19018 | Down | -0.9345970254 |
| GSE19899_A1 | Up | 0.9541588447 |
| GSE19899_A2 | Up | 2.9554245642 |
| PubMed_21979375_A1 | Up | 2.4146157043 |
| PubMed_21979375_A2 | Up | 3.2928932965 |
| GSE35957 | Down | -0.2147119795 |
| GSE36640 | Up | 0.5784002447 |
| GSE54402 | Up | 1.7594151170 |
| GSE9593 | Down | -0.3043579107 |
| GSE43922 | Up | 1.9393001430 |
| GSE24585 | Down | -0.6004827355 |
| GSE37065 | Up | 0.0585121255 |
| GSE28863_A1 | Down | -0.4373524266 |
| GSE28863_A2 | Up | 0.2200336507 |
| GSE28863_A3 | Down | -0.6735738501 |
| GSE28863_A4 | Down | -0.2698395395 |
| GSE48662 | Down | -0.1970996405 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001618 | pSILAC | Functional MTI (Weak) | 18668040 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045487 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
