HCSGD entry for GPR55
1. General information
| Official gene symbol | GPR55 |
|---|---|
| Entrez ID | 9290 |
| Gene full name | G protein-coupled receptor 55 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA TAS | molecular_function |
| GO:0004949 | Cannabinoid receptor activity | IDA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007202 | Activation of phospholipase C activity | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0035025 | Positive regulation of Rho protein signal transduction | IDA | biological_process |
| GO:0038171 | Cannabinoid signaling pathway | IDA | biological_process |
| GO:0045453 | Bone resorption | IDA | biological_process |
| GO:0045671 | Negative regulation of osteoclast differentiation | IDA | biological_process |
| GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5452229665 | 0.8527221838 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0477229100 |
| GSE13712_SHEAR | Up | 0.1500658068 |
| GSE13712_STATIC | Down | -0.1356445928 |
| GSE19018 | Down | -0.0323388058 |
| GSE19899_A1 | Down | -0.0275041627 |
| GSE19899_A2 | Up | 0.0975611814 |
| PubMed_21979375_A1 | Up | 0.0731583320 |
| PubMed_21979375_A2 | Up | 0.0192131482 |
| GSE35957 | Up | 0.0968990129 |
| GSE36640 | Up | 0.1552576030 |
| GSE54402 | Up | 0.0079028051 |
| GSE9593 | Up | 0.2675703121 |
| GSE43922 | Up | 0.0247996713 |
| GSE24585 | Up | 0.0273200711 |
| GSE37065 | Down | -0.1127389628 |
| GSE28863_A1 | Down | -0.1163647785 |
| GSE28863_A2 | Up | 0.1058085750 |
| GSE28863_A3 | Up | 0.0866311258 |
| GSE28863_A4 | Up | 0.2709461054 |
| GSE48662 | Down | -0.1620706435 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040546 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040844 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051125 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
