HCSGD entry for CD9

1. General information

Official gene symbolCD9
Entrez ID928
Gene full nameCD9 molecule
Other gene symbolsBTCC-1 DRAP-27 MIC3 MRP-1 TSPAN-29 TSPAN29
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002576Platelet degranulationTASbiological_process
GO:0005178Integrin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0006928Cellular component movementIDAbiological_process
GO:0007155Cell adhesionIDAbiological_process
GO:0007338Single fertilizationTASbiological_process
GO:0007342Fusion of sperm to egg plasma membraneIDA IEA TASbiological_process
GO:0007420Brain developmentIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0009414Response to water deprivationIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0014003Oligodendrocyte developmentIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEAcellular_component
GO:0030168Platelet activationNAS TASbiological_process
GO:0030913Paranodal junction assemblyIEA ISSbiological_process
GO:0031092Platelet alpha granule membraneTAScellular_component
GO:0032504Multicellular organism reproductionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03166579540.67907932450.41119185991.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3216191151
GSE13712_SHEARDown-0.2539594293
GSE13712_STATICDown-0.2480535275
GSE19018Up0.0210906590
GSE19899_A1Up0.6209251933
GSE19899_A2Up0.1641200231
PubMed_21979375_A1Up0.4059936141
PubMed_21979375_A2Up0.2139026905
GSE35957Down-0.0653760095
GSE36640Up0.6443679365
GSE54402Up0.2638854476
GSE9593Down-0.0836393455
GSE43922Up0.6427681559
GSE24585Down-0.1242907614
GSE37065Up0.5085665110
GSE28863_A1Down-0.4115966615
GSE28863_A2Up0.5320054439
GSE28863_A3Up0.0822419897
GSE28863_A4Up0.1902993851
GSE48662Down-0.8717077496

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

C31GDB05398 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018296MicroarrayFunctional MTI (Weak)18185580
hsa-miR-326MIMAT0000756MIRT019530Western blot;qRT-PCRFunctional MTI19883630
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

18258400CD9 antigen, MHC class I chain-related sequence A (MICA) and cell division cycle 37 homolog (CDC37) were up-regulated, and bone morphogenetic protein 4 (BMP4), dickkopf-1 (DKK1), and transcription factor 7-like 1 (TCF7L1) were down-regulated in old cells
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