HCSGD entry for CYTH3

1. General information

Official gene symbolCYTH3
Entrez ID9265
Gene full namecytohesin 3
Other gene symbolsARNO3 GRP1 PSCD3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001726RuffleIEAcellular_component
GO:0005086ARF guanyl-nucleotide exchange factor activityIBA IDA IEAmolecular_function
GO:0005547Phosphatidylinositol-3,4,5-trisphosphate bindingIDAmolecular_function
GO:0005802Trans-Golgi networkIBAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0016192Vesicle-mediated transportIBAbiological_process
GO:0030155Regulation of cell adhesionIBAbiological_process
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIDAcellular_component
GO:0032012Regulation of ARF protein signal transductionIEAbiological_process
GO:0043087Regulation of GTPase activityIBA IDAbiological_process
GO:0045785Positive regulation of cell adhesionIEAbiological_process
GO:0048193Golgi vesicle transportIMPbiological_process
GO:0090162Establishment of epithelial cell polarityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40718000080.12411718020.99999024730.6773079950

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2556987152
GSE13712_SHEARUp0.0216030102
GSE13712_STATICUp0.0219973388
GSE19018Up0.2400199571
GSE19899_A1Down-0.3047445535
GSE19899_A2Down-0.0255022176
PubMed_21979375_A1Up0.1245747283
PubMed_21979375_A2Down-0.3654494528
GSE35957Up0.3367503121
GSE36640Down-0.0073920687
GSE54402Down-0.5657839218
GSE9593Up0.4348817924
GSE43922Down-0.6648221236
GSE24585Up0.0158924223
GSE37065Down-0.6044045764
GSE28863_A1Up0.4469242252
GSE28863_A2Up0.6741373658
GSE28863_A3Up0.1280942519
GSE28863_A4Down-0.3313205147
GSE48662Up0.3314967005

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Inositol 1,3,4,5-TetrakisphosphateDB01863 EXPT01943 | DB03265
Inositol-(1,3,4,5,6)-PentakisphosphateDB03344 EXPT01818

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018199MicroarrayFunctional MTI (Weak)18185580
hsa-miR-320aMIMAT0000510MIRT044672CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.