HCSGD entry for TIMM50
1. General information
| Official gene symbol | TIMM50 |
|---|---|
| Entrez ID | 92609 |
| Gene full name | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| Other gene symbols | TIM50 TIM50L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001836 | Release of cytochrome c from mitochondria | IDA | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004721 | Phosphoprotein phosphatase activity | IDA | molecular_function |
| GO:0004722 | Protein serine/threonine phosphatase activity | IDA | molecular_function |
| GO:0004725 | Protein tyrosine phosphatase activity | IDA | molecular_function |
| GO:0005134 | Interleukin-2 receptor binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005743 | Mitochondrial inner membrane | IDA | cellular_component |
| GO:0005744 | Mitochondrial inner membrane presequence translocase complex | IEA IPI | cellular_component |
| GO:0006470 | Protein dephosphorylation | IDA | biological_process |
| GO:0006626 | Protein targeting to mitochondrion | TAS | biological_process |
| GO:0007006 | Mitochondrial membrane organization | IMP | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | IDA | biological_process |
| GO:0043021 | Ribonucleoprotein complex binding | IDA | molecular_function |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1885803655 | 0.4748564872 | 0.8464569918 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4517569484 |
| GSE13712_SHEAR | Up | 0.2190647515 |
| GSE13712_STATIC | Up | 0.4208081984 |
| GSE19018 | Down | -0.3431727269 |
| GSE19899_A1 | Down | -0.0124343260 |
| GSE19899_A2 | Up | 0.1750615076 |
| PubMed_21979375_A1 | Up | 1.2005344534 |
| PubMed_21979375_A2 | Down | -0.0072552227 |
| GSE35957 | Down | -0.2924657016 |
| GSE36640 | Down | -0.0008003998 |
| GSE54402 | Up | 0.3609816310 |
| GSE9593 | Down | -0.2405069400 |
| GSE43922 | Up | 0.2306834393 |
| GSE24585 | Down | -0.4188133943 |
| GSE37065 | Down | -0.0077049988 |
| GSE28863_A1 | Down | -0.0646590469 |
| GSE28863_A2 | Down | -0.1281825342 |
| GSE28863_A3 | Down | -0.4473208618 |
| GSE28863_A4 | Up | 0.1893410136 |
| GSE48662 | Down | -0.0739697397 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016403 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025669 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039882 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041979 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043156 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046584 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051530 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052037 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
