HCSGD entry for ATXN3L

1. General information

Official gene symbolATXN3L
Entrez ID92552
Gene full nameataxin 3-like
Other gene symbolsMJDL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001012RNA polymerase II regulatory region DNA bindingIEAmolecular_function
GO:0004221Ubiquitin thiolesterase activityIEAmolecular_function
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0005759Mitochondrial matrixIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006515Misfolded or incompletely synthesized protein catabolic processIEAbiological_process
GO:0008242Omega peptidase activityIEAmolecular_function
GO:0010810Regulation of cell-substrate adhesionIEAbiological_process
GO:0016579Protein deubiquitinationIDAbiological_process
GO:0031625Ubiquitin protein ligase bindingIEAmolecular_function
GO:0031966Mitochondrial membraneIEAcellular_component
GO:0034605Cellular response to heatIEAbiological_process
GO:0035520Monoubiquitinated protein deubiquitinationIEAbiological_process
GO:0035640Exploration behaviorIEAbiological_process
GO:0042405Nuclear inclusion bodyIEAcellular_component
GO:0043161Proteasome-mediated ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0070932Histone H3 deacetylationIEAbiological_process
GO:0071218Cellular response to misfolded proteinIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76992088450.74213110440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0121490610
GSE13712_SHEARDown-0.0752682453
GSE13712_STATICUp0.1361873169
GSE19018Up0.0155543729
GSE19899_A1Down-0.0354974429
GSE19899_A2Down-0.1120368996
PubMed_21979375_A1Up0.1563556068
PubMed_21979375_A2Up0.2948651860
GSE35957Up0.0106013014
GSE36640Down-0.0104624564
GSE54402Down-0.0986448338
GSE9593Up0.0133496449
GSE43922Up0.0174332408
GSE24585Up0.2919247634
GSE37065Down-0.0490916224
GSE28863_A1Down-0.1320736071
GSE28863_A2Up0.0950532900
GSE28863_A3Up0.0950299860
GSE28863_A4Down-0.0780025789
GSE48662Down-0.0536010949

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.