HCSGD entry for UBE2L6
1. General information
| Official gene symbol | UBE2L6 |
|---|---|
| Entrez ID | 9246 |
| Gene full name | ubiquitin-conjugating enzyme E2L 6 |
| Other gene symbols | RIG-B UBCH8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0019941 | Modification-dependent protein catabolic process | IEA | biological_process |
| GO:0032020 | ISG15-protein conjugation | IEA | biological_process |
| GO:0032480 | Negative regulation of type I interferon production | TAS | biological_process |
| GO:0042296 | ISG15 ligase activity | IEA | molecular_function |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0469826412 | 0.0447848296 | 0.4802644436 | 0.3982369932 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2139569316 |
| GSE13712_SHEAR | Up | 1.1392156812 |
| GSE13712_STATIC | Up | 1.1864053194 |
| GSE19018 | Up | 0.1952389160 |
| GSE19899_A1 | Down | -0.6086203649 |
| GSE19899_A2 | Down | -1.5408691178 |
| PubMed_21979375_A1 | Down | -1.7796588748 |
| PubMed_21979375_A2 | Down | -1.1077708276 |
| GSE35957 | Down | -0.8303990284 |
| GSE36640 | Up | 1.1102479647 |
| GSE54402 | Down | -1.0828517697 |
| GSE9593 | Up | 0.4586303731 |
| GSE43922 | Down | -0.7182658801 |
| GSE24585 | Up | 0.6542024396 |
| GSE37065 | Up | 0.4490132064 |
| GSE28863_A1 | Up | 0.1382677754 |
| GSE28863_A2 | Up | 0.2636998803 |
| GSE28863_A3 | Up | 0.0304633975 |
| GSE28863_A4 | Up | 0.1070770857 |
| GSE48662 | Up | 0.1940710696 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
