HCSGD entry for CRB3
1. General information
| Official gene symbol | CRB3 |
|---|---|
| Entrez ID | 92359 |
| Gene full name | crumbs homolog 3 (Drosophila) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0017124 | SH3 domain binding | IPI | molecular_function |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
| GO:0070830 | Tight junction assembly | TAS | biological_process |
| GO:0072659 | Protein localization to plasma membrane | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4462338323 | 0.8609057483 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0349957731 |
| GSE13712_SHEAR | Down | -0.0614355086 |
| GSE13712_STATIC | Up | 0.0055961548 |
| GSE19018 | Up | 0.0318356968 |
| GSE19899_A1 | Up | 0.1503160277 |
| GSE19899_A2 | Up | 0.1136982602 |
| PubMed_21979375_A1 | Up | 0.1837380759 |
| PubMed_21979375_A2 | Down | -0.0232431913 |
| GSE35957 | Up | 0.1064144245 |
| GSE36640 | Up | 0.0385524220 |
| GSE54402 | Up | 0.0779630739 |
| GSE9593 | Down | -0.1673980046 |
| GSE43922 | Up | 0.1810409935 |
| GSE24585 | Down | -0.1020280825 |
| GSE37065 | Down | -0.0126222422 |
| GSE28863_A1 | Down | -0.1700531743 |
| GSE28863_A2 | Down | -0.1472711314 |
| GSE28863_A3 | Up | 0.4746858708 |
| GSE28863_A4 | Up | 0.1122005904 |
| GSE48662 | Up | 0.0010455157 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017389 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
