HCSGD entry for IL32
1. General information
| Official gene symbol | IL32 |
|---|---|
| Entrez ID | 9235 |
| Gene full name | interleukin 32 |
| Other gene symbols | IL-32alpha IL-32beta IL-32delta IL-32gamma NK4 TAIF TAIFa TAIFb TAIFc TAIFd |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0006952 | Defense response | TAS | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007155 | Cell adhesion | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0035478553 | 0.9172831047 | 0.1618317241 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3088323215 |
| GSE13712_SHEAR | Up | 0.4903936805 |
| GSE13712_STATIC | Up | 0.7820518775 |
| GSE19018 | Up | 2.1725579469 |
| GSE19899_A1 | Down | -0.3760433700 |
| GSE19899_A2 | Up | 0.6800838701 |
| PubMed_21979375_A1 | Up | 0.6919848643 |
| PubMed_21979375_A2 | Down | -0.0389296173 |
| GSE35957 | Up | 1.0005660294 |
| GSE36640 | Up | 0.1731262366 |
| GSE54402 | Down | -0.2776249428 |
| GSE9593 | Up | 0.5695371438 |
| GSE43922 | Up | 0.1152966520 |
| GSE24585 | Up | 0.4739950006 |
| GSE37065 | Up | 0.6477970309 |
| GSE28863_A1 | Down | -0.1693829507 |
| GSE28863_A2 | Up | 0.5831274629 |
| GSE28863_A3 | Up | 0.4991881710 |
| GSE28863_A4 | Down | -0.0362713199 |
| GSE48662 | Up | 0.0125286229 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-205-5p | MIMAT0000266 | MIRT005564 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 20737563 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027524 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25548483 | The hepatocyte SASP included characteristic factors such as interleukin (IL)-8 and IL-6, as well as novel components such as SAA4, IL-32 and Fibrinogen, which were validated by qPCR and/or chemokine protein array |
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