HCSGD entry for DLG5
1. General information
| Official gene symbol | DLG5 |
|---|---|
| Entrez ID | 9231 |
| Gene full name | discs, large homolog 5 (Drosophila) |
| Other gene symbols | LP-DLG P-DLG5 PDLG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005913 | Cell-cell adherens junction | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008013 | Beta-catenin binding | IDA | molecular_function |
| GO:0008092 | Cytoskeletal protein binding | IDA | molecular_function |
| GO:0008285 | Negative regulation of cell proliferation | TAS | biological_process |
| GO:0016337 | Cell-cell adhesion | NAS | biological_process |
| GO:0030159 | Receptor signaling complex scaffold activity | NAS | molecular_function |
| GO:0035556 | Intracellular signal transduction | NAS | biological_process |
| GO:0042981 | Regulation of apoptotic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6235938946 | 0.5196553284 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0305846909 |
| GSE13712_SHEAR | Up | 0.1046941804 |
| GSE13712_STATIC | Up | 0.3245891331 |
| GSE19018 | Up | 0.0328431136 |
| GSE19899_A1 | Down | -0.2771409515 |
| GSE19899_A2 | Down | -0.2008710628 |
| PubMed_21979375_A1 | Down | -0.5387117173 |
| PubMed_21979375_A2 | Down | -0.1879774066 |
| GSE35957 | Up | 0.0962643243 |
| GSE36640 | Down | -0.0221006503 |
| GSE54402 | Down | -0.1150325685 |
| GSE9593 | Down | -0.1205916297 |
| GSE43922 | Up | 0.0177372807 |
| GSE24585 | Up | 0.0157605547 |
| GSE37065 | Down | -0.0589399048 |
| GSE28863_A1 | Up | 0.4271016434 |
| GSE28863_A2 | Up | 0.4275120386 |
| GSE28863_A3 | Up | 0.0075043763 |
| GSE28863_A4 | Down | -0.0415415526 |
| GSE48662 | Up | 0.0339379109 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004847 | Luciferase reporter assay//qRT-PCR//Reporter assay;Microarray;Other | Functional MTI | 19074876 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024569 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-484 | MIMAT0002174 | MIRT042178 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050554 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
