HCSGD entry for NOLC1
1. General information
| Official gene symbol | NOLC1 |
|---|---|
| Entrez ID | 9221 |
| Gene full name | nucleolar and coiled-body phosphoprotein 1 |
| Other gene symbols | NOPP130 NOPP140 NS5ATP13 P130 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006364 | RRNA processing | TAS | biological_process |
| GO:0007000 | Nucleolus organization | IEA | biological_process |
| GO:0007049 | Cell cycle | TAS | biological_process |
| GO:0007067 | Mitosis | TAS | biological_process |
| GO:0015030 | Cajal body | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0199033775 | 0.3895765358 | 0.3419311807 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0503147568 |
| GSE13712_SHEAR | Up | 0.3073472993 |
| GSE13712_STATIC | Up | 0.4154495547 |
| GSE19018 | Down | -0.4499970980 |
| GSE19899_A1 | Up | 0.3704250257 |
| GSE19899_A2 | Up | 0.9785814425 |
| PubMed_21979375_A1 | Up | 1.2728789825 |
| PubMed_21979375_A2 | Up | 0.8515441270 |
| GSE35957 | Down | -0.6654604856 |
| GSE36640 | Down | -1.2797538134 |
| GSE54402 | Up | 0.4414203711 |
| GSE9593 | Down | -0.5791048453 |
| GSE43922 | Up | 0.7234194323 |
| GSE24585 | Down | -0.7165111754 |
| GSE37065 | Down | -0.0380715399 |
| GSE28863_A1 | Up | 0.2035415402 |
| GSE28863_A2 | Up | 0.4128379389 |
| GSE28863_A3 | Down | -0.2017810149 |
| GSE28863_A4 | Up | 0.2250419474 |
| GSE48662 | Up | 0.1804479901 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019859 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020682 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027538 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032259 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038083 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039653 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042221 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042908 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043949 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-365a-3p | MIMAT0000710 | MIRT044030 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-195-5p | MIMAT0000461 | MIRT044865 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046772 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051504 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052391 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
