HCSGD entry for VAPA
1. General information
| Official gene symbol | VAPA |
|---|---|
| Entrez ID | 9218 |
| Gene full name | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa |
| Other gene symbols | VAP-33 VAP-A VAP33 hVAP-33 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004871 | Signal transducer activity | IMP | molecular_function |
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005923 | Tight junction | IDA | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0007165 | Signal transduction | IMP | biological_process |
| GO:0008219 | Cell death | IMP | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030148 | Sphingolipid biosynthetic process | TAS | biological_process |
| GO:0031175 | Neuron projection development | IMP | biological_process |
| GO:0031982 | Vesicle | IDA | cellular_component |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0061025 | Membrane fusion | TAS | biological_process |
| GO:0070972 | Protein localization to endoplasmic reticulum | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9411806466 | 0.1129674480 | 0.9999902473 | 0.6441542894 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0505856956 |
| GSE13712_SHEAR | Down | -0.3054313286 |
| GSE13712_STATIC | Down | -0.2525848833 |
| GSE19018 | Down | -0.0303352588 |
| GSE19899_A1 | Down | -0.2029467575 |
| GSE19899_A2 | Down | -0.3646583535 |
| PubMed_21979375_A1 | Down | -0.0952088714 |
| PubMed_21979375_A2 | Down | -0.2736948721 |
| GSE35957 | Up | 0.0546188402 |
| GSE36640 | Down | -0.3365949832 |
| GSE54402 | Down | -0.0526233204 |
| GSE9593 | Down | -0.1211504435 |
| GSE43922 | Up | 0.1146029928 |
| GSE24585 | Down | -0.2782987921 |
| GSE37065 | Down | -0.0403038423 |
| GSE28863_A1 | Up | 0.3793907743 |
| GSE28863_A2 | Up | 0.1974170027 |
| GSE28863_A3 | Down | -0.7039022452 |
| GSE28863_A4 | Up | 0.1418952430 |
| GSE48662 | Down | -0.0727760785 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT016124 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027325 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
