HCSGD entry for LARGE
1. General information
| Official gene symbol | LARGE |
|---|---|
| Entrez ID | 9215 |
| Gene full name | like-glycosyltransferase |
| Other gene symbols | MDC1D MDDGA6 MDDGB6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0006044 | N-acetylglucosamine metabolic process | TAS | biological_process |
| GO:0006486 | Protein glycosylation | IEA | biological_process |
| GO:0006688 | Glycosphingolipid biosynthetic process | TAS | biological_process |
| GO:0008375 | Acetylglucosaminyltransferase activity | TAS | molecular_function |
| GO:0009101 | Glycoprotein biosynthetic process | TAS | biological_process |
| GO:0016757 | Transferase activity, transferring glycosyl groups | IEA TAS | molecular_function |
| GO:0030173 | Integral component of Golgi membrane | TAS | cellular_component |
| GO:0046716 | Muscle cell cellular homeostasis | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2367162912 | 0.5831373542 | 0.9205983304 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0797090924 |
| GSE13712_SHEAR | Down | -0.0585245212 |
| GSE13712_STATIC | Down | -0.0457194692 |
| GSE19018 | Down | -0.3333339770 |
| GSE19899_A1 | Down | -0.0700252209 |
| GSE19899_A2 | Down | -0.3657697755 |
| PubMed_21979375_A1 | Down | -0.5372927060 |
| PubMed_21979375_A2 | Up | 0.1371027898 |
| GSE35957 | Up | 0.0673278026 |
| GSE36640 | Up | 0.0371449497 |
| GSE54402 | Up | 0.2027671556 |
| GSE9593 | Up | 0.2707508053 |
| GSE43922 | Up | 0.0280785344 |
| GSE24585 | Down | -0.1251369820 |
| GSE37065 | Up | 0.3755556479 |
| GSE28863_A1 | Down | -0.1702330358 |
| GSE28863_A2 | Up | 0.4783608459 |
| GSE28863_A3 | Up | 0.4581580686 |
| GSE28863_A4 | Up | 0.3067302253 |
| GSE48662 | Down | -0.1627961197 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050713 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
