HCSGD entry for DEDD
1. General information
| Official gene symbol | DEDD |
|---|---|
| Entrez ID | 9191 |
| Gene full name | death effector domain containing |
| Other gene symbols | CASP8IP1 DEDD1 DEFT FLDED1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005730 | Nucleolus | ISS | cellular_component |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008625 | Extrinsic apoptotic signaling pathway via death domain receptors | IEA | biological_process |
| GO:0042177 | Negative regulation of protein catabolic process | IEA | biological_process |
| GO:0042981 | Regulation of apoptotic process | IEA | biological_process |
| GO:0046697 | Decidualization | IEA | biological_process |
| GO:1901837 | Negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8907170320 | 0.2114720261 | 0.9999902473 | 0.8874609694 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0341811676 |
| GSE13712_SHEAR | Up | 0.1276583231 |
| GSE13712_STATIC | Down | -0.1437740424 |
| GSE19018 | Up | 0.1544902717 |
| GSE19899_A1 | Down | -0.1293149620 |
| GSE19899_A2 | Up | 0.0001798560 |
| PubMed_21979375_A1 | Down | -0.3441372729 |
| PubMed_21979375_A2 | Down | -0.7019436868 |
| GSE35957 | Down | -0.2378659917 |
| GSE36640 | Down | -0.3003119206 |
| GSE54402 | Up | 0.2190979695 |
| GSE9593 | Up | 0.0271595231 |
| GSE43922 | Down | -0.0224357292 |
| GSE24585 | Up | 0.2146497550 |
| GSE37065 | Up | 0.0518216055 |
| GSE28863_A1 | Down | -0.2105473541 |
| GSE28863_A2 | Down | -0.0771776879 |
| GSE28863_A3 | Down | -0.4160916021 |
| GSE28863_A4 | Down | -0.1868112437 |
| GSE48662 | Up | 0.3997570736 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030548 | Western blot | Functional MTI | 20138800 |
| hsa-miR-935 | MIMAT0004978 | MIRT036647 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040264 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052117 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
