HCSGD entry for DDX21
1. General information
| Official gene symbol | DDX21 |
|---|---|
| Entrez ID | 9188 |
| Gene full name | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| Other gene symbols | GUA GURDB RH-II/GU RH-II/GuA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003725 | Double-stranded RNA binding | IEA | molecular_function |
| GO:0004004 | ATP-dependent RNA helicase activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0009615 | Response to virus | IEA | biological_process |
| GO:0043330 | Response to exogenous dsRNA | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0310225941 | 0.1626248775 | 0.4074579341 | 0.7789697289 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0892016497 |
| GSE13712_SHEAR | Up | 0.3630439882 |
| GSE13712_STATIC | Up | 0.3620551294 |
| GSE19018 | Down | -1.4729426915 |
| GSE19899_A1 | Up | 0.4880033869 |
| GSE19899_A2 | Up | 0.4669255037 |
| PubMed_21979375_A1 | Up | 1.2902473044 |
| PubMed_21979375_A2 | Up | 0.6491479874 |
| GSE35957 | Down | -0.1668710660 |
| GSE36640 | Down | -0.2409507275 |
| GSE54402 | Up | 0.4449841918 |
| GSE9593 | Down | -0.6254316637 |
| GSE43922 | Up | 0.4239126079 |
| GSE24585 | Down | -0.8338110674 |
| GSE37065 | Down | -0.2031362423 |
| GSE28863_A1 | Up | 0.2765049079 |
| GSE28863_A2 | Up | 0.3941353884 |
| GSE28863_A3 | Up | 0.0802966463 |
| GSE28863_A4 | Up | 0.2080553689 |
| GSE48662 | Down | -0.6854389759 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016482 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-29c-3p | MIMAT0000681 | MIRT020395 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025491 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031736 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032414 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036938 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038053 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043386 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045036 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046685 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048581 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
