HCSGD entry for OSMR


1. General information

Official gene symbolOSMR
Entrez ID9180
Gene full nameoncostatin M receptor
Other gene symbolsOSMRB PLCA1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002675Positive regulation of acute inflammatory responseICbiological_process
GO:0004924Oncostatin-M receptor activityIDAmolecular_function
GO:0005900Oncostatin-M receptor complexIDAcellular_component
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0008284Positive regulation of cell proliferationIGIbiological_process
GO:0019221Cytokine-mediated signaling pathwayIDAbiological_process
GO:0019838Growth factor bindingIPImolecular_function
GO:0034097Response to cytokineIDAbiological_process
GO:0038165Oncostatin-M-mediated signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00167269860.90684861520.10943762381.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2559120356
GSE13712_SHEARDown-0.2429783813
GSE13712_STATICDown-0.2651538681
GSE19018Up0.0971842579
GSE19899_A1Up0.7851283298
GSE19899_A2Up1.6065971558
PubMed_21979375_A1Up1.0466090593
PubMed_21979375_A2Up1.3425965139
GSE35957Up0.0255875218
GSE36640Up0.1256751352
GSE54402Up0.5689031344
GSE9593Up0.8393357772
GSE43922Up0.5519976083
GSE24585Up0.8996968725
GSE37065Down-0.0267212062
GSE28863_A1Up0.9762967714
GSE28863_A2Up1.2246533321
GSE28863_A3Down-0.0724722743
GSE28863_A4Down-0.4984446850
GSE48662Up0.2645367806

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016997MicroarrayFunctional MTI (Weak)18185580
hsa-miR-98-5pMIMAT0000096MIRT027517MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.