HCSGD entry for CD3G

1. General information

Official gene symbolCD3G
Entrez ID917
Gene full nameCD3g molecule, gamma (CD3-TCR complex)
Other gene symbolsCD3-GAMMA T3G
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004888Transmembrane signaling receptor activityIEA IMPmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0006461Protein complex assemblyNASbiological_process
GO:0007163Establishment or maintenance of cell polarityIMPbiological_process
GO:0007166Cell surface receptor signaling pathwayIEA IMPbiological_process
GO:0015031Protein transportIMPbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030159Receptor signaling complex scaffold activityNASmolecular_function
GO:0031295T cell costimulationTASbiological_process
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0042101T cell receptor complexNAScellular_component
GO:0042105Alpha-beta T cell receptor complexIEAcellular_component
GO:0042110T cell activationNASbiological_process
GO:0042608T cell receptor bindingNASmolecular_function
GO:0045087Innate immune responseTASbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0050776Regulation of immune responseTASbiological_process
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0070228Regulation of lymphocyte apoptotic processIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81620379920.64724990310.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1258381422
GSE13712_SHEARUp0.0193634673
GSE13712_STATICDown-0.2010286441
GSE19018Up0.1777708281
GSE19899_A1Up0.0968292808
GSE19899_A2Down-0.0895274124
PubMed_21979375_A1Down-0.1722682257
PubMed_21979375_A2Down-0.0859919727
GSE35957Up0.0998705699
GSE36640Up0.0782080626
GSE54402Up0.0587872988
GSE9593Up0.1417500614
GSE43922Up0.0115638150
GSE24585Up0.0933336967
GSE37065Down-0.0756157983
GSE28863_A1Down-0.0355237161
GSE28863_A2Down-0.0548088146
GSE28863_A3Up0.1476127956
GSE28863_A4Down-0.0922911620
GSE48662Up0.1201745553

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MuromonabDB00075 BTD00005 | BIOD00005

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.