HCSGD entry for NEXN
1. General information
| Official gene symbol | NEXN |
|---|---|
| Entrez ID | 91624 |
| Gene full name | nexilin (F actin binding protein) |
| Other gene symbols | CMH20 NELIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005924 | Cell-substrate adherens junction | IEA | cellular_component |
| GO:0008307 | Structural constituent of muscle | IMP | molecular_function |
| GO:0030018 | Z disc | ISS | cellular_component |
| GO:0030334 | Regulation of cell migration | IDA IEA | biological_process |
| GO:0051015 | Actin filament binding | IDA IEA | molecular_function |
| GO:0051493 | Regulation of cytoskeleton organization | IEP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6093442992 | 0.0013001292 | 0.9999902473 | 0.0692726721 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.4337184329 |
| GSE13712_SHEAR | Up | 0.9182173206 |
| GSE13712_STATIC | Up | 0.5052520378 |
| GSE19018 | Down | -0.4507375919 |
| GSE19899_A1 | Down | -1.8250506116 |
| GSE19899_A2 | Down | -0.9400966769 |
| PubMed_21979375_A1 | Down | -2.2998995389 |
| PubMed_21979375_A2 | Down | -1.5165154881 |
| GSE35957 | Up | 0.9240372608 |
| GSE36640 | Up | 0.1689924294 |
| GSE54402 | Down | -2.0741447837 |
| GSE9593 | Up | 0.4803581406 |
| GSE43922 | Down | -1.1825131662 |
| GSE24585 | Down | -0.0629075455 |
| GSE37065 | Down | -0.3359652524 |
| GSE28863_A1 | Down | -0.0199630550 |
| GSE28863_A2 | Up | 0.0898000674 |
| GSE28863_A3 | Up | 0.1440764522 |
| GSE28863_A4 | Down | -0.2632913485 |
| GSE48662 | Down | -0.3543087149 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
