HCSGD entry for CD3D

1. General information

Official gene symbolCD3D
Entrez ID915
Gene full nameCD3d molecule, delta (CD3-TCR complex)
Other gene symbolsCD3-DELTA T3D
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0004888Transmembrane signaling receptor activityIC IEAmolecular_function
GO:0005737CytoplasmNAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007166Cell surface receptor signaling pathwayIC IEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030217T cell differentiationIDAbiological_process
GO:0031295T cell costimulationTASbiological_process
GO:0042101T cell receptor complexIDA NAScellular_component
GO:0042105Alpha-beta T cell receptor complexIEAcellular_component
GO:0045059Positive thymic T cell selectionISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0050776Regulation of immune responseTASbiological_process
GO:0050852T cell receptor signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35143157930.90922968350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0271651972
GSE13712_SHEARDown-0.0275760326
GSE13712_STATICDown-0.0433757619
GSE19018Up0.1115404198
GSE19899_A1Down-0.0934277580
GSE19899_A2Up0.2142143648
PubMed_21979375_A1Up0.1108186100
PubMed_21979375_A2Down-0.1060716286
GSE35957Up0.2072196132
GSE36640Down-0.1391574254
GSE54402Up0.1320643123
GSE9593Up0.0608515239
GSE43922Up0.0262625168
GSE24585Down-0.0532013353
GSE37065Up0.0154232649
GSE28863_A1Up0.1228250893
GSE28863_A2Up0.2301802793
GSE28863_A3Up0.2820477046
GSE28863_A4Up0.1860310125
GSE48662Up0.1815251535

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MuromonabDB00075 BTD00005 | BIOD00005
BlinatumomabDB09052 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.