HCSGD entry for PKDCC
1. General information
| Official gene symbol | PKDCC |
|---|---|
| Entrez ID | 91461 |
| Gene full name | protein kinase domain containing, cytoplasmic |
| Other gene symbols | SGK493 Vlk |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | IEA | biological_process |
| GO:0004672 | Protein kinase activity | ISS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005794 | Golgi apparatus | ISS | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030282 | Bone mineralization | IEA | biological_process |
| GO:0030501 | Positive regulation of bone mineralization | ISS | biological_process |
| GO:0032332 | Positive regulation of chondrocyte differentiation | ISS | biological_process |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0042997 | Negative regulation of Golgi to plasma membrane protein transport | ISS | biological_process |
| GO:0048286 | Lung alveolus development | ISS | biological_process |
| GO:0048566 | Embryonic digestive tract development | ISS | biological_process |
| GO:0060021 | Palate development | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9873319631 | 0.0001852399 | 0.9999902473 | 0.0245860000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2060376091 |
| GSE13712_SHEAR | Down | -1.1154820466 |
| GSE13712_STATIC | Down | -0.5876089924 |
| GSE19018 | Down | -0.3364561680 |
| GSE19899_A1 | Down | -1.9210900011 |
| GSE19899_A2 | Down | -2.0965087212 |
| PubMed_21979375_A1 | Down | -2.8912563551 |
| PubMed_21979375_A2 | Down | -2.1901463253 |
| GSE35957 | Up | 0.3198953725 |
| GSE36640 | Down | -2.2162255499 |
| GSE54402 | Down | -2.7636733596 |
| GSE9593 | Down | -0.0092308530 |
| GSE43922 | Down | -1.0373976833 |
| GSE24585 | Down | -0.4617102984 |
| GSE37065 | Down | -0.1862415855 |
| GSE28863_A1 | Up | 0.0266077037 |
| GSE28863_A2 | Down | -0.3063596460 |
| GSE28863_A3 | Up | 0.3703010413 |
| GSE28863_A4 | Down | -0.0887101050 |
| GSE48662 | Up | 0.0560851228 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049360 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050335 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
