HCSGD entry for CBFA2T2
1. General information
| Official gene symbol | CBFA2T2 |
|---|---|
| Entrez ID | 9139 |
| Gene full name | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| Other gene symbols | EHT MTGR1 ZMYND3 p85 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0010976 | Positive regulation of neuron projection development | IDA | biological_process |
| GO:0010977 | Negative regulation of neuron projection development | ISS | biological_process |
| GO:0030855 | Epithelial cell differentiation | IEA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2374521675 | 0.9207992402 | 0.9226140517 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0530769352 |
| GSE13712_SHEAR | Up | 0.0327863699 |
| GSE13712_STATIC | Down | -0.1317940461 |
| GSE19018 | Up | 0.0249623339 |
| GSE19899_A1 | Up | 0.0457240712 |
| GSE19899_A2 | Up | 0.0704622944 |
| PubMed_21979375_A1 | Down | -0.0324346987 |
| PubMed_21979375_A2 | Up | 0.1417086856 |
| GSE35957 | Down | -0.3164181619 |
| GSE36640 | Up | 0.3458922069 |
| GSE54402 | Up | 0.0851563172 |
| GSE9593 | Down | -0.0663165186 |
| GSE43922 | Up | 0.0501993244 |
| GSE24585 | Up | 0.4895441187 |
| GSE37065 | Up | 0.2564505471 |
| GSE28863_A1 | Up | 0.4489143122 |
| GSE28863_A2 | Up | 0.1614663489 |
| GSE28863_A3 | Down | -0.1758872646 |
| GSE28863_A4 | Down | -0.1135510355 |
| GSE48662 | Up | 0.2239448640 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-101-3p | MIMAT0000099 | MIRT027387 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044277 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049423 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
