HCSGD entry for KCNQ4


1. General information

Official gene symbolKCNQ4
Entrez ID9132
Gene full namepotassium voltage-gated channel, KQT-like subfamily, member 4
Other gene symbolsDFNA2 DFNA2A KV7.4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005249Voltage-gated potassium channel activityIEAmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005267Potassium channel activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0009925Basal plasma membraneIEAcellular_component
GO:0042472Inner ear morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27970306980.89334621400.97640112731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0053327015
GSE13712_SHEARDown-0.0695528271
GSE13712_STATICDown-0.0083909825
GSE19018Up0.0637586840
GSE19899_A1Down-0.0974400268
GSE19899_A2Up0.0039556196
PubMed_21979375_A1Up0.0435199551
PubMed_21979375_A2Up0.2114205350
GSE35957Up0.1299248402
GSE36640Up0.2179165086
GSE54402Up0.0305814127
GSE9593Down-0.0004752148
GSE43922Up0.0687127582
GSE24585Down-0.2469426544
GSE37065Down-0.0723845066
GSE28863_A1Down-0.0091596153
GSE28863_A2Up0.0965435711
GSE28863_A3Up0.3512992492
GSE28863_A4Up0.0144664141
GSE48662Up1.3192540016

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

ICA-105665DB06089 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.