HCSGD entry for PRPF4
1. General information
| Official gene symbol | PRPF4 |
|---|---|
| Entrez ID | 9128 |
| Gene full name | PRP4 pre-mRNA processing factor 4 homolog (yeast) |
| Other gene symbols | HPRP4 HPRP4P PRP4 Prp4p |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000375 | RNA splicing, via transesterification reactions | NAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IC NAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006396 | RNA processing | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0071001 | U4/U6 snRNP | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0326868432 | 0.3139351658 | 0.4168364341 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2733576616 |
| GSE13712_SHEAR | Up | 0.3158457895 |
| GSE13712_STATIC | Up | 0.1710466062 |
| GSE19018 | Down | -0.8030586640 |
| GSE19899_A1 | Up | 0.4846494389 |
| GSE19899_A2 | Up | 0.5310163365 |
| PubMed_21979375_A1 | Up | 1.0847935906 |
| PubMed_21979375_A2 | Up | 0.7834517467 |
| GSE35957 | Down | -0.6585628482 |
| GSE36640 | Down | -1.1582997637 |
| GSE54402 | Up | 0.5634521701 |
| GSE9593 | Down | -0.1219366770 |
| GSE43922 | Up | 0.8066510528 |
| GSE24585 | Down | -0.3792050930 |
| GSE37065 | Down | -0.0810214399 |
| GSE28863_A1 | Up | 0.1691331920 |
| GSE28863_A2 | Up | 0.3903941159 |
| GSE28863_A3 | Down | -0.2490260528 |
| GSE28863_A4 | Up | 0.0041792650 |
| GSE48662 | Down | -0.2374998981 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
