HCSGD entry for PKMYT1
1. General information
| Official gene symbol | PKMYT1 |
|---|---|
| Entrez ID | 9088 |
| Gene full name | protein kinase, membrane associated tyrosine/threonine 1 |
| Other gene symbols | MYT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000079 | Regulation of cyclin-dependent protein serine/threonine kinase activity | TAS | biological_process |
| GO:0000082 | G1/S transition of mitotic cell cycle | TAS | biological_process |
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0004672 | Protein kinase activity | IEA TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | TAS | cellular_component |
| GO:0007067 | Mitosis | TAS | biological_process |
| GO:0007088 | Regulation of mitosis | TAS | biological_process |
| GO:0010923 | Negative regulation of phosphatase activity | IDA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016301 | Kinase activity | IDA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051726 | Regulation of cell cycle | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9364579727 | 0.0080517799 | 0.9999902473 | 0.1786663016 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3501595520 |
| GSE13712_SHEAR | Up | 0.0948222499 |
| GSE13712_STATIC | Up | 0.0012056344 |
| GSE19018 | Up | 0.1680109665 |
| GSE19899_A1 | Down | -0.4937087820 |
| GSE19899_A2 | Down | -0.9358937667 |
| PubMed_21979375_A1 | Down | -0.9481527092 |
| PubMed_21979375_A2 | Down | -0.9025257612 |
| GSE35957 | Down | -0.4115462714 |
| GSE36640 | Down | -0.7886261702 |
| GSE54402 | Down | -0.1654691702 |
| GSE9593 | Down | -0.4846991424 |
| GSE43922 | Down | -0.1769250243 |
| GSE24585 | Down | -0.1675565094 |
| GSE37065 | Down | -0.2062459950 |
| GSE28863_A1 | Up | 0.1714890231 |
| GSE28863_A2 | Up | 0.5384351597 |
| GSE28863_A3 | Up | 0.1123018633 |
| GSE28863_A4 | Up | 0.0607686031 |
| GSE48662 | Down | -1.5623868143 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016346 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042806 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050725 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
