HCSGD entry for CLDN1
1. General information
| Official gene symbol | CLDN1 |
|---|---|
| Entrez ID | 9076 |
| Gene full name | claudin 1 |
| Other gene symbols | CLD1 ILVASC SEMP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005923 | Tight junction | ISS | cellular_component |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0016328 | Lateral plasma membrane | IEA | cellular_component |
| GO:0016338 | Calcium-independent cell-cell adhesion | ISS | biological_process |
| GO:0042802 | Identical protein binding | ISS | molecular_function |
| GO:0045216 | Cell-cell junction organization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000495232 | 0.9868184074 | 0.0188913043 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3861451155 |
| GSE13712_SHEAR | Up | 1.8761401265 |
| GSE13712_STATIC | Up | 2.1609094578 |
| GSE19018 | Up | 0.9523455046 |
| GSE19899_A1 | Up | 0.9571504820 |
| GSE19899_A2 | Up | 5.2727773623 |
| PubMed_21979375_A1 | Up | 2.6815757859 |
| PubMed_21979375_A2 | Up | 2.6493921084 |
| GSE35957 | Down | -0.3300610035 |
| GSE36640 | Up | 3.2820598137 |
| GSE54402 | Down | -0.4429686988 |
| GSE9593 | Up | 0.0147603616 |
| GSE43922 | Up | 1.7773094327 |
| GSE24585 | Down | -0.1285395601 |
| GSE37065 | Up | 1.0336346066 |
| GSE28863_A1 | Down | -0.2161579944 |
| GSE28863_A2 | Up | 0.1501029074 |
| GSE28863_A3 | Up | 0.2940557281 |
| GSE28863_A4 | Down | -0.0452271069 |
| GSE48662 | Up | 0.5314725128 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001558 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017510 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-375 | MIMAT0000728 | MIRT019768 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-29b-3p | MIMAT0000100 | MIRT048360 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
