HCSGD entry for CCNT2


1. General information

Official gene symbolCCNT2
Entrez ID905
Gene full namecyclin T2
Other gene symbolsCYCT2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000079Regulation of cyclin-dependent protein serine/threonine kinase activityIEAbiological_process
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006351Transcription, DNA-templatedTASbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0007179Transforming growth factor beta receptor signaling pathwayTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0051301Cell divisionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.70100041410.12774508570.99999024730.6884476658

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1442143653
GSE13712_SHEARUp0.1190023275
GSE13712_STATICUp0.1537024608
GSE19018Down-0.3480753973
GSE19899_A1Up0.0149387671
GSE19899_A2Down-0.0638341168
PubMed_21979375_A1Up0.0201854923
PubMed_21979375_A2Up0.1420710154
GSE35957Down-0.0531134273
GSE36640Up0.0140458892
GSE54402Down-0.0190398984
GSE9593Down-0.0544796802
GSE43922Down-0.0402445228
GSE24585Up0.6220566466
GSE37065Up0.1791927727
GSE28863_A1Down-0.0586456396
GSE28863_A2Up0.3851780837
GSE28863_A3Down-0.9088750969
GSE28863_A4Down-0.4140738120
GSE48662Down-0.6086385704

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT001801Luciferase reporter assay//Reporter assay;OtherNon-Functional MTI15131085
hsa-miR-29c-3pMIMAT0000681MIRT020397SequencingFunctional MTI (Weak)20371350
hsa-miR-196a-5pMIMAT0000226MIRT026073SequencingFunctional MTI (Weak)20371350
hsa-miR-22-3pMIMAT0000077MIRT030643SequencingFunctional MTI (Weak)20371350
hsa-miR-877-5pMIMAT0004949MIRT037376CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041987CLASHFunctional MTI (Weak)23622248
hsa-miR-423-3pMIMAT0001340MIRT042585CLASHFunctional MTI (Weak)23622248
hsa-miR-204-5pMIMAT0000265MIRT047016CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.