HCSGD entry for AIP
1. General information
| Official gene symbol | AIP |
|---|---|
| Entrez ID | 9049 |
| Gene full name | aryl hydrocarbon receptor interacting protein |
| Other gene symbols | ARA9 FKBP16 FKBP37 SMTPHN XAP-2 XAP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0006626 | Protein targeting to mitochondrion | IDA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008134 | Transcription factor binding | TAS | molecular_function |
| GO:0010738 | Regulation of protein kinase A signaling | IEA | biological_process |
| GO:0022417 | Protein maturation by protein folding | IDA | biological_process |
| GO:0036004 | GAF domain binding | IDA | molecular_function |
| GO:0051082 | Unfolded protein binding | IDA | molecular_function |
| GO:0051344 | Negative regulation of cyclic-nucleotide phosphodiesterase activity | IEA | biological_process |
| GO:2001141 | Regulation of RNA biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9850976217 | 0.0148415296 | 0.9999902473 | 0.2396723483 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0274913980 |
| GSE13712_SHEAR | Down | -0.5041950548 |
| GSE13712_STATIC | Down | -0.8218618932 |
| GSE19018 | Up | 0.0124097815 |
| GSE19899_A1 | Down | -0.5341141023 |
| GSE19899_A2 | Down | -0.8329971568 |
| PubMed_21979375_A1 | Down | -0.2850346864 |
| PubMed_21979375_A2 | Down | -1.1177508900 |
| GSE35957 | Down | -0.7459633047 |
| GSE36640 | Down | -0.4123956135 |
| GSE54402 | Down | -0.0070913106 |
| GSE9593 | Down | -0.0858916217 |
| GSE43922 | Down | -0.1163774406 |
| GSE24585 | Down | -0.2261211059 |
| GSE37065 | Up | 0.0339715565 |
| GSE28863_A1 | Down | -0.0248434736 |
| GSE28863_A2 | Down | -0.3833051797 |
| GSE28863_A3 | Down | -0.1398848625 |
| GSE28863_A4 | Up | 0.0092284588 |
| GSE48662 | Up | 0.3185564043 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 8734329 | Malondialdehyde (MDA), a lipid peroxidation product, reacts with free amino groups of proteins to give amino-3-iminopropene (AIP) bridges which are immunogenic |
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