HCSGD entry for SH2D2A
1. General information
| Official gene symbol | SH2D2A |
|---|---|
| Entrez ID | 9047 |
| Gene full name | SH2 domain containing 2A |
| Other gene symbols | F2771 SCAP TSAD VRAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008283 | Cell proliferation | IEA | biological_process |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0030154 | Cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0214051062 | 0.9712407469 | 0.3525680851 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3123563444 |
| GSE13712_SHEAR | Up | 0.8739708845 |
| GSE13712_STATIC | Up | 0.2554966952 |
| GSE19018 | Up | 0.1340567045 |
| GSE19899_A1 | Up | 0.1908491051 |
| GSE19899_A2 | Up | 0.3654973819 |
| PubMed_21979375_A1 | Up | 0.6462804519 |
| PubMed_21979375_A2 | Up | 0.7922879389 |
| GSE35957 | Down | -0.0809551232 |
| GSE36640 | Down | -0.1795683988 |
| GSE54402 | Up | 0.8650734136 |
| GSE9593 | Down | -0.1229438784 |
| GSE43922 | Up | 0.3583449919 |
| GSE24585 | Up | 0.2737621355 |
| GSE37065 | Up | 0.1734401744 |
| GSE28863_A1 | Down | -0.1962267375 |
| GSE28863_A2 | Up | 0.0269174109 |
| GSE28863_A3 | Up | 0.3515828350 |
| GSE28863_A4 | Up | 0.0089161665 |
| GSE48662 | Up | 0.3892160152 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
