HCSGD entry for ERI1
1. General information
| Official gene symbol | ERI1 |
|---|---|
| Entrez ID | 90459 |
| Gene full name | exoribonuclease 1 |
| Other gene symbols | 3'HEXO HEXO THEX1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0005730 | Nucleolus | IDA ISS | cellular_component |
| GO:0005737 | Cytoplasm | IDA ISS | cellular_component |
| GO:0008408 | 3'-5' exonuclease activity | IDA | molecular_function |
| GO:0019843 | RRNA binding | ISS | molecular_function |
| GO:0031047 | Gene silencing by RNA | IEA | biological_process |
| GO:0031125 | RRNA 3'-end processing | ISS | biological_process |
| GO:0043022 | Ribosome binding | ISS | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0071044 | Histone mRNA catabolic process | IMP | biological_process |
| GO:0071204 | Histone pre-mRNA 3'end processing complex | ISS | cellular_component |
| GO:0071207 | Histone pre-mRNA stem-loop binding | ISS | molecular_function |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5199358383 | 0.0619248319 | 0.9999902473 | 0.4693234955 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0531448634 |
| GSE13712_SHEAR | Down | -0.1741746773 |
| GSE13712_STATIC | Down | -0.0869246826 |
| GSE19018 | Down | -0.2218505432 |
| GSE19899_A1 | Up | 0.1345945725 |
| GSE19899_A2 | Down | -0.4180861995 |
| PubMed_21979375_A1 | Up | 0.4848256957 |
| PubMed_21979375_A2 | Down | -0.3161656156 |
| GSE35957 | Down | -0.3545193605 |
| GSE36640 | Down | -1.5127170580 |
| GSE54402 | Up | 0.7959501480 |
| GSE9593 | Down | -0.0207878698 |
| GSE43922 | Up | 0.0632000515 |
| GSE24585 | Up | 0.1174669108 |
| GSE37065 | Up | 0.0109874489 |
| GSE28863_A1 | Down | -0.1935836419 |
| GSE28863_A2 | Up | 0.7455624067 |
| GSE28863_A3 | Down | -0.6308245328 |
| GSE28863_A4 | Down | -0.0753398922 |
| GSE48662 | Down | -0.6847469001 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020545 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047993 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
