HCSGD entry for SPAG9


1. General information

Official gene symbolSPAG9
Entrez ID9043
Gene full namesperm associated antigen 9
Other gene symbolsCT89 HLC-6 HLC4 JIP-4 JIP4 JLP PHET PIG6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001669Acrosomal vesicleIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007257Activation of JUN kinase activityIEAbiological_process
GO:0007283SpermatogenesisTASbiological_process
GO:0008432JUN kinase bindingIEAmolecular_function
GO:0016021Integral component of membraneTAScellular_component
GO:0019894Kinesin bindingIEAmolecular_function
GO:0030335Positive regulation of cell migrationIMPbiological_process
GO:0042147Retrograde transport, endosome to GolgiIDAbiological_process
GO:0042692Muscle cell differentiationTASbiological_process
GO:0045666Positive regulation of neuron differentiationIEAbiological_process
GO:0048273Mitogen-activated protein kinase p38 bindingIEAmolecular_function
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0051146Striated muscle cell differentiationIEAbiological_process
GO:0051149Positive regulation of muscle cell differentiationTASbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
GO:0090074Negative regulation of protein homodimerization activityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02918455230.84136794950.39657542591.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1412939924
GSE13712_SHEARUp0.7363761332
GSE13712_STATICUp0.5154199221
GSE19018Up0.1309891099
GSE19899_A1Down-0.1640444451
GSE19899_A2Down-0.2348919725
PubMed_21979375_A1Down-0.2446657391
PubMed_21979375_A2Down-0.3164766652
GSE35957Up0.4230106300
GSE36640Up0.0408045749
GSE54402Down-0.3626454866
GSE9593Up0.3064713517
GSE43922Down-0.1435693719
GSE24585Up0.7351733750
GSE37065Up0.4043639733
GSE28863_A1Up0.7088845995
GSE28863_A2Up0.9421289064
GSE28863_A3Down-0.0284899513
GSE28863_A4Up0.0898633964
GSE48662Up0.0818322186

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017842MicroarrayFunctional MTI (Weak)18185580
hsa-miR-375MIMAT0000728MIRT019876MicroarrayFunctional MTI (Weak)20215506
hsa-miR-9-5pMIMAT0000441MIRT021369MicroarrayFunctional MTI (Weak)17612493
hsa-miR-122-5pMIMAT0000421MIRT023290MicroarrayFunctional MTI (Weak)17612493
hsa-miR-215-5pMIMAT0000272MIRT024300MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026494MicroarrayFunctional MTI (Weak)19074876
hsa-miR-877-3pMIMAT0004950MIRT036882CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041411CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041911CLASHFunctional MTI (Weak)23622248
hsa-miR-27b-3pMIMAT0000419MIRT046181CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051618CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.