HCSGD entry for MED30
1. General information
| Official gene symbol | MED30 |
|---|---|
| Entrez ID | 90390 |
| Gene full name | mediator complex subunit 30 |
| Other gene symbols | MED30S THRAP6 TRAP25 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001104 | RNA polymerase II transcription cofactor activity | IDA | molecular_function |
| GO:0003712 | Transcription cofactor activity | IDA | molecular_function |
| GO:0004872 | Receptor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | IDA TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016592 | Mediator complex | IDA | cellular_component |
| GO:0019827 | Stem cell maintenance | IEA | biological_process |
| GO:0030374 | Ligand-dependent nuclear receptor transcription coactivator activity | NAS | molecular_function |
| GO:0030518 | Intracellular steroid hormone receptor signaling pathway | IDA | biological_process |
| GO:0030521 | Androgen receptor signaling pathway | IDA | biological_process |
| GO:0042809 | Vitamin D receptor binding | NAS | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046966 | Thyroid hormone receptor binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9776666426 | 0.0145499829 | 0.9999902473 | 0.2371331889 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4449912210 |
| GSE13712_SHEAR | Down | -0.3767505575 |
| GSE13712_STATIC | Down | -0.2834407075 |
| GSE19018 | Up | 0.0139288854 |
| GSE19899_A1 | Down | -0.8379285399 |
| GSE19899_A2 | Down | -0.5992163341 |
| PubMed_21979375_A1 | Down | -0.5931999351 |
| PubMed_21979375_A2 | Down | -1.3552138003 |
| GSE35957 | Down | -0.4971973332 |
| GSE36640 | Down | -1.4699144987 |
| GSE54402 | Up | 0.2742465271 |
| GSE9593 | Down | -0.3278166495 |
| GSE43922 | Up | 0.0611160603 |
| GSE24585 | Down | -0.0802800257 |
| GSE37065 | Down | -0.0231119081 |
| GSE28863_A1 | Up | 0.1242202220 |
| GSE28863_A2 | Up | 0.2631778241 |
| GSE28863_A3 | Down | -0.0502253226 |
| GSE28863_A4 | Down | -0.0781283129 |
| GSE48662 | Down | -0.3672598745 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
