HCSGD entry for CCNH

1. General information

Official gene symbolCCNH
Entrez ID902
Gene full namecyclin H
Other gene symbolsCAK p34 p37
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000079Regulation of cyclin-dependent protein serine/threonine kinase activityIEAbiological_process
GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000718Nucleotide-excision repair, DNA damage removalTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusTAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005675Holo TFIIH complexIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006360Transcription from RNA polymerase I promoterTASbiological_process
GO:0006361Transcription initiation from RNA polymerase I promoterTASbiological_process
GO:0006362Transcription elongation from RNA polymerase I promoterTASbiological_process
GO:0006363Termination of RNA polymerase I transcriptionTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0006468Protein phosphorylationIDAbiological_process
GO:0008094DNA-dependent ATPase activityIDAmolecular_function
GO:0008353RNA polymerase II carboxy-terminal domain kinase activityIDAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016301Kinase activityIEAmolecular_function
GO:0016538Cyclin-dependent protein serine/threonine kinase regulator activityIEAmolecular_function
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0019907Cyclin-dependent protein kinase activating kinase holoenzyme complexIDAcellular_component
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
GO:0070985TFIIK complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77782233960.05317238710.99999024730.4345080410

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0194709437
GSE13712_SHEARUp0.0677534899
GSE13712_STATICUp0.1581248483
GSE19018Down-0.2615823284
GSE19899_A1Down-0.0816473503
GSE19899_A2Down-0.0864352323
PubMed_21979375_A1Up0.7643934764
PubMed_21979375_A2Down-0.2395590604
GSE35957Down-0.1602789902
GSE36640Down-0.4582639515
GSE54402Up0.3744891150
GSE9593Down-0.1278274308
GSE43922Down-0.1653475389
GSE24585Up0.1365324439
GSE37065Up0.0642091489
GSE28863_A1Up0.0888836255
GSE28863_A2Up0.0426538112
GSE28863_A3Down-1.2263958420
GSE28863_A4Down-0.3067632966
GSE48662Down-0.5064603456

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1301-3pMIMAT0005797MIRT035962CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.