HCSGD entry for KCNH7
1. General information
| Official gene symbol | KCNH7 |
|---|---|
| Entrez ID | 90134 |
| Gene full name | potassium voltage-gated channel, subfamily H (eag-related), member 7 |
| Other gene symbols | ERG3 HERG3 Kv11.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005242 | Inward rectifier potassium channel activity | IEA | molecular_function |
| GO:0005249 | Voltage-gated potassium channel activity | IBA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IBA | cellular_component |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007623 | Circadian rhythm | IEA | biological_process |
| GO:0042391 | Regulation of membrane potential | IBA | biological_process |
| GO:0051291 | Protein heterooligomerization | IEA | biological_process |
| GO:0071805 | Potassium ion transmembrane transport | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7203537252 | 0.8973319289 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0179103494 |
| GSE13712_SHEAR | Down | -0.0599344388 |
| GSE13712_STATIC | Up | 0.0045488298 |
| GSE19018 | Up | 0.0028113301 |
| GSE19899_A1 | Up | 0.1383040846 |
| GSE19899_A2 | Up | 0.0335201334 |
| PubMed_21979375_A1 | Down | -0.0062384877 |
| PubMed_21979375_A2 | Up | 0.0014303634 |
| GSE35957 | Up | 0.0696299076 |
| GSE36640 | Up | 0.0933952433 |
| GSE54402 | Up | 0.1294756189 |
| GSE9593 | Down | -0.0560288148 |
| GSE43922 | Up | 0.1249264647 |
| GSE24585 | Down | -0.0726814258 |
| GSE37065 | Up | 0.0341112766 |
| GSE28863_A1 | Down | -0.1177902412 |
| GSE28863_A2 | Up | 0.0887188192 |
| GSE28863_A3 | Up | 0.1681739446 |
| GSE28863_A4 | Up | 0.0624495081 |
| GSE48662 | Up | 0.0106911306 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Ibutilide | DB00308 | APRD01025 |
| Prazosin | DB00457 | APRD00020 |
| Miconazole | DB01110 | APRD01115 |
| Terazosin | DB01162 | APRD00667 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
