HCSGD entry for PHLDB2
1. General information
| Official gene symbol | PHLDB2 |
|---|---|
| Entrez ID | 90102 |
| Gene full name | pleckstrin homology-like domain, family B, member 2 |
| Other gene symbols | LL5b LL5beta |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0045111 | Intermediate filament cytoskeleton | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8181539227 | 0.0215477603 | 0.9999902473 | 0.2837565455 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1453432375 |
| GSE13712_SHEAR | Up | 0.8121006811 |
| GSE13712_STATIC | Up | 0.3820892696 |
| GSE19018 | Down | -0.2132624337 |
| GSE19899_A1 | Down | -0.1350584090 |
| GSE19899_A2 | Down | -0.3030277482 |
| PubMed_21979375_A1 | Down | -0.5812690550 |
| PubMed_21979375_A2 | Down | -0.4016764202 |
| GSE35957 | Up | 0.4230879989 |
| GSE36640 | Down | -0.1398247824 |
| GSE54402 | Down | -1.0495104763 |
| GSE9593 | Down | -0.0284474434 |
| GSE43922 | Down | -0.4794370973 |
| GSE24585 | Up | 0.2658482352 |
| GSE37065 | Down | -0.4925319819 |
| GSE28863_A1 | Up | 0.4146358796 |
| GSE28863_A2 | Up | 0.2299162195 |
| GSE28863_A3 | Down | -0.6468114732 |
| GSE28863_A4 | Down | -0.4373274594 |
| GSE48662 | Down | -0.3037860499 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001432 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023789 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
