HCSGD entry for LIMD1

1. General information

Official gene symbolLIMD1
Entrez ID8994
Gene full nameLIM domains containing 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000932Cytoplasmic mRNA processing bodyIDAcellular_component
GO:0001666Response to hypoxiaIDAbiological_process
GO:0002076Osteoblast developmentISSbiological_process
GO:0003714Transcription corepressor activityISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005912Adherens junctionIDAcellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0007010Cytoskeleton organizationIMPbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008360Regulation of cell shapeIMPbiological_process
GO:0016310PhosphorylationIDAbiological_process
GO:0016442RISC complexIDAcellular_component
GO:0016477Cell migrationIMPbiological_process
GO:0033962Cytoplasmic mRNA processing body assemblyIMPbiological_process
GO:0035195Gene silencing by miRNAIMPbiological_process
GO:0035331Negative regulation of hippo signalingIDAbiological_process
GO:0045668Negative regulation of osteoblast differentiationISSbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDA IMPbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayISSbiological_process
GO:2000637Positive regulation of gene silencing by miRNAIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97470829760.02637500850.99999024730.3113258961

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1881301353
GSE13712_SHEARUp0.2284026895
GSE13712_STATICUp0.2485163906
GSE19018Down-0.1247489462
GSE19899_A1Down-0.4491229664
GSE19899_A2Down-0.3927948454
PubMed_21979375_A1Down-0.5548765310
PubMed_21979375_A2Down-0.4518563585
GSE35957Down-0.1285651236
GSE36640Down-0.5218177949
GSE54402Down-0.4668284233
GSE9593Up0.2730303325
GSE43922Down-0.5152865937
GSE24585Down-0.6425481683
GSE37065Up0.0754643184
GSE28863_A1Up0.0310443359
GSE28863_A2Up0.1221783119
GSE28863_A3Down-0.3831951065
GSE28863_A4Down-0.1364193190
GSE48662Up0.0580016776

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022837MicroarrayFunctional MTI (Weak)18668037
hsa-miR-24-3pMIMAT0000080MIRT030543SequencingFunctional MTI (Weak)20371350
hsa-miR-455-3pMIMAT0004784MIRT037903CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049139CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.