HCSGD entry for LHX4
1. General information
| Official gene symbol | LHX4 |
|---|---|
| Entrez ID | 89884 |
| Gene full name | LIM homeobox 4 |
| Other gene symbols | CPHD4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001890 | Placenta development | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008045 | Motor neuron axon guidance | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0009887 | Organ morphogenesis | IEA | biological_process |
| GO:0021526 | Medial motor column neuron differentiation | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8577933665 | 0.6607447589 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0347109902 |
| GSE13712_SHEAR | Down | -0.0906749358 |
| GSE13712_STATIC | Up | 0.0264274868 |
| GSE19018 | Up | 0.0496958836 |
| GSE19899_A1 | Up | 0.1037442000 |
| GSE19899_A2 | Up | 0.0404136664 |
| PubMed_21979375_A1 | Down | -0.2116706549 |
| PubMed_21979375_A2 | Down | -0.0702140902 |
| GSE35957 | Up | 0.0158490297 |
| GSE36640 | Up | 0.1176201223 |
| GSE54402 | Down | -0.1603319594 |
| GSE9593 | Up | 0.1278232053 |
| GSE43922 | Up | 0.0219351386 |
| GSE24585 | Down | -0.4073188979 |
| GSE37065 | Down | -0.0260899946 |
| GSE28863_A1 | Down | -0.0431922720 |
| GSE28863_A2 | Up | 0.0860207585 |
| GSE28863_A3 | Up | 0.2320646377 |
| GSE28863_A4 | Up | 0.0351092733 |
| GSE48662 | Up | 0.0437167564 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023725 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
