HCSGD entry for NAV2
1. General information
| Official gene symbol | NAV2 |
|---|---|
| Entrez ID | 89797 |
| Gene full name | neuron navigator 2 |
| Other gene symbols | HELAD1 POMFIL2 RAINB1 STEERIN2 UNC53H2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003025 | Regulation of systemic arterial blood pressure by baroreceptor feedback | IEA | biological_process |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005614 | Interstitial matrix | IEA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0007605 | Sensory perception of sound | IEA | biological_process |
| GO:0007608 | Sensory perception of smell | IEA | biological_process |
| GO:0007626 | Locomotory behavior | IEA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0021554 | Optic nerve development | IEA | biological_process |
| GO:0021563 | Glossopharyngeal nerve development | IEA | biological_process |
| GO:0021564 | Vagus nerve development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1873196193 | 0.1936137571 | 0.8439602430 | 0.8531013385 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0379680743 |
| GSE13712_SHEAR | Up | 0.4522213715 |
| GSE13712_STATIC | Up | 0.2147051368 |
| GSE19018 | Down | -0.1435806130 |
| GSE19899_A1 | Down | -0.0582768559 |
| GSE19899_A2 | Down | -0.4176840494 |
| PubMed_21979375_A1 | Down | -0.4186352700 |
| PubMed_21979375_A2 | Down | -0.1523552060 |
| GSE35957 | Down | -0.0425415005 |
| GSE36640 | Down | -1.1853301339 |
| GSE54402 | Down | -0.1089539367 |
| GSE9593 | Up | 0.0105970348 |
| GSE43922 | Down | -0.4343336936 |
| GSE24585 | Down | -0.1825383855 |
| GSE37065 | Up | 0.4816513822 |
| GSE28863_A1 | Up | 0.8572275868 |
| GSE28863_A2 | Up | 0.8886912997 |
| GSE28863_A3 | Up | 0.1647771582 |
| GSE28863_A4 | Up | 0.2751969906 |
| GSE48662 | Down | -0.4005109529 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027632 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051065 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23949429 | Interestingly, the polycomb repressive complex -2 (PCRC2) target genes Kiss1r, Nav2 and Hsf4 were hypermethylated with age |
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