HCSGD entry for CDK5R2

1. General information

Official gene symbolCDK5R2
Entrez ID8941
Gene full namecyclin-dependent kinase 5, regulatory subunit 2 (p39)
Other gene symbolsNCK5AI P39 p39nck5ai
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000079Regulation of cyclin-dependent protein serine/threonine kinase activityTASbiological_process
GO:0001764Neuron migrationIEAbiological_process
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0008289Lipid bindingIEAmolecular_function
GO:0016533Cyclin-dependent protein kinase 5 holoenzyme complexIEAcellular_component
GO:0016534Cyclin-dependent protein kinase 5 activator activityIEAmolecular_function
GO:0021549Cerebellum developmentIEAbiological_process
GO:0021722Superior olivary nucleus maturationIEAbiological_process
GO:0021766Hippocampus developmentIEAbiological_process
GO:0021819Layer formation in cerebral cortexIEAbiological_process
GO:0045956Positive regulation of calcium ion-dependent exocytosisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14797796440.95448339350.77073998811.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0504336280
GSE13712_SHEARDown-0.0137701010
GSE13712_STATICUp0.0042905147
GSE19018Up0.2096425982
GSE19899_A1Up0.0770507232
GSE19899_A2Down-0.0632584627
PubMed_21979375_A1Up0.2895033596
PubMed_21979375_A2Up0.0073614104
GSE35957Up0.0137770541
GSE36640Down-0.0003675996
GSE54402Up0.1321351363
GSE9593Up0.0633300271
GSE43922Up0.0808362824
GSE24585Up0.1247481409
GSE37065Down-0.0658098275
GSE28863_A1Up0.0161123209
GSE28863_A2Up0.2790479979
GSE28863_A3Up0.3801118216
GSE28863_A4Up0.1239940650
GSE48662Up0.8398655245

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT020417MicroarrayFunctional MTI (Weak)17242205
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.