HCSGD entry for CACNA1H

1. General information

Official gene symbolCACNA1H
Entrez ID8912
Gene full namecalcium channel, voltage-dependent, T type, alpha 1H subunit
Other gene symbolsCACNA1HB Cav3.2 ECA6 EIG6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005216Ion channel activityIEAmolecular_function
GO:0005891Voltage-gated calcium channel complexIEAcellular_component
GO:0005901CaveolaIEAcellular_component
GO:0006810TransportTASbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0007517Muscle organ developmentNASbiological_process
GO:0007520Myoblast fusionTASbiological_process
GO:0008016Regulation of heart contractionTASbiological_process
GO:0008332Low voltage-gated calcium channel activityIDAmolecular_function
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0032342Aldosterone biosynthetic processIMPbiological_process
GO:0032870Cellular response to hormone stimulusIEPbiological_process
GO:0034651Cortisol biosynthetic processIMPbiological_process
GO:0035865Cellular response to potassium ionIEPbiological_process
GO:0042383SarcolemmaIEAcellular_component
GO:0042391Regulation of membrane potentialIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0070509Calcium ion importIDAbiological_process
GO:0097110Scaffold protein bindingIPImolecular_function
GO:2000344Positive regulation of acrosome reactionIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63417541890.86856453780.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0834542475
GSE13712_SHEARDown-0.1386857369
GSE13712_STATICUp0.0467984504
GSE19018Down-0.0692567639
GSE19899_A1Down-0.0216665249
GSE19899_A2Up0.1629257059
PubMed_21979375_A1Down-0.0650702137
PubMed_21979375_A2Down-0.1690487242
GSE35957Down-0.0377121516
GSE36640Up0.0302842654
GSE54402Up0.0192656952
GSE9593Up0.0534728900
GSE43922Up0.0503584408
GSE24585Up0.0454927534
GSE37065Up0.0378368971
GSE28863_A1Down-0.0758643489
GSE28863_A2Up0.0515376325
GSE28863_A3Up0.4296368256
GSE28863_A4Up0.0872192175
GSE48662Up0.2624786500

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

IsradipineDB00270 APRD00298
CinnarizineDB00568 APRD00332
ZonisamideDB00909 APRD00004
NitrendipineDB01054 APRD00421
NifedipineDB01115 APRD00590
AmiodaroneDB01118 APRD00288
BepridilDB01244 APRD00727
MibefradilDB01388 -
FlunarizineDB04841 -
SpironolactoneDB00421 APRD01234

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.