HCSGD entry for AP1S2
1. General information
| Official gene symbol | AP1S2 |
|---|---|
| Entrez ID | 8905 |
| Gene full name | adaptor-related protein complex 1, sigma 2 subunit |
| Other gene symbols | MGC:1902 MRX59 MRXS21 MRXSF SIGMA1B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0005765 | Lysosomal membrane | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005905 | Coated pit | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006892 | Post-Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030117 | Membrane coat | IEA | cellular_component |
| GO:0030119 | AP-type membrane coat adaptor complex | TAS | cellular_component |
| GO:0030659 | Cytoplasmic vesicle membrane | TAS | cellular_component |
| GO:0032588 | Trans-Golgi network membrane | TAS | cellular_component |
| GO:0050690 | Regulation of defense response to virus by virus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3169040918 | 0.0201036929 | 0.9999902473 | 0.2750905132 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3819881072 |
| GSE13712_SHEAR | Up | 0.2890503477 |
| GSE13712_STATIC | Up | 0.4383795134 |
| GSE19018 | Up | 0.8980417481 |
| GSE19899_A1 | Down | -0.4462819919 |
| GSE19899_A2 | Up | 0.2003024379 |
| PubMed_21979375_A1 | Down | -1.0377432533 |
| PubMed_21979375_A2 | Down | -0.7428483378 |
| GSE35957 | Down | -0.5414363651 |
| GSE36640 | Down | -0.2057498458 |
| GSE54402 | Up | 1.0020584586 |
| GSE9593 | Down | -0.6130095260 |
| GSE43922 | Down | -0.3749273578 |
| GSE24585 | Down | -0.8677742112 |
| GSE37065 | Up | 0.0758414354 |
| GSE28863_A1 | Down | -0.1892317057 |
| GSE28863_A2 | Down | -0.7288674177 |
| GSE28863_A3 | Down | -0.5362226266 |
| GSE28863_A4 | Up | 0.0587767973 |
| GSE48662 | Down | -0.1826871471 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT005816 | Luciferase reporter assay//Microarray//qRT-PCR | Functional MTI | 21282569 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024614 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026570 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
