HCSGD entry for DDX18
1. General information
| Official gene symbol | DDX18 |
|---|---|
| Entrez ID | 8886 |
| Gene full name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 |
| Other gene symbols | MrDb |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004004 | ATP-dependent RNA helicase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0008152 | Metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8143180844 | 0.1128894685 | 0.9999902473 | 0.6438491224 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0293744656 |
| GSE13712_SHEAR | Down | -0.0212543125 |
| GSE13712_STATIC | Up | 0.1327466397 |
| GSE19018 | Down | -0.7356038698 |
| GSE19899_A1 | Down | -0.1503363936 |
| GSE19899_A2 | Up | 0.0843656129 |
| PubMed_21979375_A1 | Up | 0.6047790835 |
| PubMed_21979375_A2 | Up | 0.0356729636 |
| GSE35957 | Down | -0.5173693277 |
| GSE36640 | Down | -0.7568930296 |
| GSE54402 | Up | 0.2890855080 |
| GSE9593 | Down | -0.7212152568 |
| GSE43922 | Up | 0.0534565098 |
| GSE24585 | Down | -0.5975498062 |
| GSE37065 | Up | 0.0896307464 |
| GSE28863_A1 | Up | 0.0557493585 |
| GSE28863_A2 | Up | 0.4057212766 |
| GSE28863_A3 | Down | -0.1784301356 |
| GSE28863_A4 | Down | -0.0212646973 |
| GSE48662 | Down | -0.1957705424 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-3p | MIMAT0000762 | MIRT042964 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT045851 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048605 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051780 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052091 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052470 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
