HCSGD entry for SLC5A6
1. General information
| Official gene symbol | SLC5A6 |
|---|---|
| Entrez ID | 8884 |
| Gene full name | solute carrier family 5 (sodium-dependent vitamin transporter), member 6 |
| Other gene symbols | SMVT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006768 | Biotin metabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0008523 | Sodium-dependent multivitamin transmembrane transporter activity | IEA | molecular_function |
| GO:0012506 | Vesicle membrane | IEA | cellular_component |
| GO:0015878 | Biotin transport | IEA | biological_process |
| GO:0015887 | Pantothenate transmembrane transport | IEA | biological_process |
| GO:0015939 | Pantothenate metabolic process | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031526 | Brush border membrane | IEA | cellular_component |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5304692299 | 0.0756648874 | 0.9999902473 | 0.5192949426 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0262893490 |
| GSE13712_SHEAR | Down | -0.0802923792 |
| GSE13712_STATIC | Up | 0.1622680826 |
| GSE19018 | Down | -0.2822726231 |
| GSE19899_A1 | Up | 0.0105374478 |
| GSE19899_A2 | Down | -0.0494767992 |
| PubMed_21979375_A1 | Down | -0.5748851247 |
| PubMed_21979375_A2 | Up | 1.1629226196 |
| GSE35957 | Down | -0.6192692760 |
| GSE36640 | Down | -0.7285216201 |
| GSE54402 | Up | 0.6549376663 |
| GSE9593 | Down | -0.8717007396 |
| GSE43922 | Up | 0.3514476614 |
| GSE24585 | Down | -0.6708901648 |
| GSE37065 | Down | -0.0427142137 |
| GSE28863_A1 | Down | -0.1637041231 |
| GSE28863_A2 | Up | 0.3912769754 |
| GSE28863_A3 | Down | -0.4216567559 |
| GSE28863_A4 | Down | -0.0378461874 |
| GSE48662 | Down | -0.0076140701 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027678 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030522 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046193 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
