HCSGD entry for CDC16

1. General information

Official gene symbolCDC16
Entrez ID8881
Gene full namecell division cycle 16
Other gene symbolsANAPC6 APC6 CUT9
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005680Anaphase-promoting complexIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005819SpindleTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005876Spindle microtubuleIDAcellular_component
GO:0007067MitosisIEAbiological_process
GO:0007088Regulation of mitosisTASbiological_process
GO:0007094Mitotic spindle assembly checkpointTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0051301Cell divisionIEAbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0070979Protein K11-linked ubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80430219980.25038825270.99999024730.9607097959

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0548290343
GSE13712_SHEARDown-0.0298484030
GSE13712_STATICUp0.1246808429
GSE19018Up0.2000750496
GSE19899_A1Down-0.1965010529
GSE19899_A2Up0.2070011271
PubMed_21979375_A1Down-0.1141824769
PubMed_21979375_A2Down-0.2692205771
GSE35957Up0.1233985519
GSE36640Up0.4495842670
GSE54402Down-0.1195320001
GSE9593Up0.1973828627
GSE43922Down-0.2421523399
GSE24585Down-0.2705716071
GSE37065Down-0.1390618860
GSE28863_A1Up0.0488357483
GSE28863_A2Down-0.1891355735
GSE28863_A3Down-0.5187146240
GSE28863_A4Up0.1602531886
GSE48662Down-0.0682610813

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-93-5pMIMAT0000093MIRT048910CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.