HCSGD entry for SYNJ2
1. General information
| Official gene symbol | SYNJ2 |
|---|---|
| Entrez ID | 8871 |
| Gene full name | synaptojanin 2 |
| Other gene symbols | INPP5H |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004439 | Phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0042578 | Phosphoric ester hydrolase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046856 | Phosphatidylinositol dephosphorylation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7946296797 | 0.0327958436 | 0.9999902473 | 0.3418690693 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2667571260 |
| GSE13712_SHEAR | Up | 0.5254913238 |
| GSE13712_STATIC | Up | 0.5221527712 |
| GSE19018 | Down | -0.5747356549 |
| GSE19899_A1 | Down | -0.1882438732 |
| GSE19899_A2 | Down | -0.6196241168 |
| PubMed_21979375_A1 | Down | -1.3687358623 |
| PubMed_21979375_A2 | Down | -0.8517794100 |
| GSE35957 | Down | -0.2160325431 |
| GSE36640 | Down | -0.4970027141 |
| GSE54402 | Up | 0.1912643332 |
| GSE9593 | Down | -0.1821525355 |
| GSE43922 | Down | -0.5815185896 |
| GSE24585 | Down | -0.1386042749 |
| GSE37065 | Up | 0.3084496011 |
| GSE28863_A1 | Up | 0.1774573133 |
| GSE28863_A2 | Up | 0.6771702063 |
| GSE28863_A3 | Down | -0.0035865249 |
| GSE28863_A4 | Down | -0.2351148774 |
| GSE48662 | Down | -0.1405764594 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036063 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042886 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
