HCSGD entry for ST3GAL5


1. General information

Official gene symbolST3GAL5
Entrez ID8869
Gene full nameST3 beta-galactoside alpha-2,3-sialyltransferase 5
Other gene symbolsSATI SIAT9 SIATGM3S ST3GalV
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneNAScellular_component
GO:0001574Ganglioside biosynthetic processNASbiological_process
GO:0004513Neolactotetraosylceramide alpha-2,3-sialyltransferase activityTASmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006486Protein glycosylationIEAbiological_process
GO:0006688Glycosphingolipid biosynthetic processTASbiological_process
GO:0008373Sialyltransferase activityTASmolecular_function
GO:0016021Integral component of membraneTAScellular_component
GO:0016757Transferase activity, transferring glycosyl groupsIEAmolecular_function
GO:0030173Integral component of Golgi membraneIEAcellular_component
GO:0047291Lactosylceramide alpha-2,3-sialyltransferase activityIDAmolecular_function
GO:0097503SialylationIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04572863870.81044148400.47427372981.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3243639803
GSE13712_SHEARDown-0.6304566296
GSE13712_STATICDown-0.1323131448
GSE19018Down-0.0987212533
GSE19899_A1Up0.3661344994
GSE19899_A2Up0.0459538879
PubMed_21979375_A1Up0.0174412282
PubMed_21979375_A2Up0.5665780901
GSE35957Down-0.0069619818
GSE36640Up0.8810946160
GSE54402Down-0.3621390115
GSE9593Up0.3147093954
GSE43922Up0.4614342646
GSE24585Up0.3508536420
GSE37065Up0.0265089249
GSE28863_A1Up0.7767378740
GSE28863_A2Up0.0779110262
GSE28863_A3Down-0.2934880618
GSE28863_A4Up0.0998782257
GSE48662Up0.1989061537

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

99mTc-14 F7 MabDB05867 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018189MicroarrayFunctional MTI (Weak)18185580
hsa-miR-186-5pMIMAT0000456MIRT045016CLASHFunctional MTI (Weak)23622248
hsa-miR-7-5pMIMAT0000252MIRT047769CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.