HCSGD entry for STK19
1. General information
| Official gene symbol | STK19 |
|---|---|
| Entrez ID | 8859 |
| Gene full name | serine/threonine kinase 19 |
| Other gene symbols | D6S60 D6S60E G11 HLA-RP1 RP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5729673721 | 0.6744511607 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0619703441 |
| GSE13712_SHEAR | Down | -0.2368912367 |
| GSE13712_STATIC | Down | -0.2161646899 |
| GSE19018 | Up | 0.0129434845 |
| GSE19899_A1 | Down | -0.1850914877 |
| GSE19899_A2 | Up | 0.0366151835 |
| PubMed_21979375_A1 | Up | 0.0918913695 |
| PubMed_21979375_A2 | Down | -0.1390438137 |
| GSE35957 | Up | 0.0154304297 |
| GSE36640 | Up | 0.4316775509 |
| GSE54402 | Down | -0.0931244246 |
| GSE9593 | Up | 0.1510077083 |
| GSE43922 | Up | 0.0363197643 |
| GSE24585 | Up | 0.1049768940 |
| GSE37065 | Down | -0.2467007533 |
| GSE28863_A1 | Up | 0.4078045789 |
| GSE28863_A2 | Up | 0.4367543717 |
| GSE28863_A3 | Up | 0.0361346747 |
| GSE28863_A4 | Down | -0.0635145004 |
| GSE48662 | Up | 0.3451586075 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT044241 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 21238584 | The expression of a G protein gamma subunit, gamma11, capable of translocation from the plasma membrane to the Golgi complex on receptor activation increases with senescence |
| 21238584 | Knockdown of gamma11 or overexpression of a dominant negative gamma3 subunit inhibits Golgi dispersal induced by senescence |
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