HCSGD entry for ASAP2
1. General information
| Official gene symbol | ASAP2 |
|---|---|
| Entrez ID | 8853 |
| Gene full name | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 |
| Other gene symbols | AMAP2 CENTB3 DDEF2 PAG3 PAP Pap-alpha SHAG1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0008047 | Enzyme activator activity | TAS | molecular_function |
| GO:0008060 | ARF GTPase activator activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
| GO:0032580 | Golgi cisterna membrane | IEA | cellular_component |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8528189886 | 0.0456157251 | 0.9999902473 | 0.4005978993 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3089753122 |
| GSE13712_SHEAR | Up | 0.0834806718 |
| GSE13712_STATIC | Up | 0.0753925843 |
| GSE19018 | Up | 0.1308391072 |
| GSE19899_A1 | Down | -0.0742160922 |
| GSE19899_A2 | Down | -1.0637822654 |
| PubMed_21979375_A1 | Down | -0.2844941990 |
| PubMed_21979375_A2 | Down | -0.7556609530 |
| GSE35957 | Up | 0.1912743376 |
| GSE36640 | Up | 0.2214287917 |
| GSE54402 | Down | -0.1637065645 |
| GSE9593 | Up | 0.2497550304 |
| GSE43922 | Down | -0.3690952979 |
| GSE24585 | Down | -0.5027333185 |
| GSE37065 | Down | -0.0294034547 |
| GSE28863_A1 | Down | -0.0363264787 |
| GSE28863_A2 | Up | 0.5974437532 |
| GSE28863_A3 | Down | -0.7058886996 |
| GSE28863_A4 | Down | -0.0142013662 |
| GSE48662 | Down | -0.2179039284 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019707 | Microarray | Functional MTI (Weak) | 20215506 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
