HCSGD entry for LIN7A
1. General information
| Official gene symbol | LIN7A |
|---|---|
| Entrez ID | 8825 |
| Gene full name | lin-7 homolog A (C. elegans) |
| Other gene symbols | LIN-7A LIN7 MALS-1 TIP-33 VELI1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0006887 | Exocytosis | IEA | biological_process |
| GO:0007269 | Neurotransmitter secretion | IEA | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0048489 | Synaptic vesicle transport | IEA | biological_process |
| GO:0048839 | Inner ear development | IEA | biological_process |
| GO:0097016 | L27 domain binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9582317199 | 0.0001995669 | 0.9999902473 | 0.0248226415 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0313882674 |
| GSE13712_SHEAR | Down | -1.4987332726 |
| GSE13712_STATIC | Down | -0.6989988547 |
| GSE19018 | Up | 0.3196672456 |
| GSE19899_A1 | Down | -0.8668020385 |
| GSE19899_A2 | Down | -3.2693724038 |
| PubMed_21979375_A1 | Down | -3.3373337931 |
| PubMed_21979375_A2 | Down | -4.1142307883 |
| GSE35957 | Down | -0.5669127650 |
| GSE36640 | Down | -0.7441996744 |
| GSE54402 | Down | -1.0070034266 |
| GSE9593 | Down | -0.1460081062 |
| GSE43922 | Down | -1.9640092768 |
| GSE24585 | Up | 0.9102315334 |
| GSE37065 | Down | -0.1435756098 |
| GSE28863_A1 | Down | -0.6134027555 |
| GSE28863_A2 | Down | -0.2047966240 |
| GSE28863_A3 | Down | -0.5278522879 |
| GSE28863_A4 | Up | 0.2773488812 |
| GSE48662 | Down | -0.5285428450 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017177 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022330 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
