HCSGD entry for HESX1
1. General information
| Official gene symbol | HESX1 |
|---|---|
| Entrez ID | 8820 |
| Gene full name | HESX homeobox 1 |
| Other gene symbols | ANF CPHD5 RPX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007420 | Brain development | TAS | biological_process |
| GO:0008022 | Protein C-terminus binding | IEA | molecular_function |
| GO:0030916 | Otic vesicle formation | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0043584 | Nose development | IEA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0047485 | Protein N-terminus binding | IEA | molecular_function |
| GO:0048853 | Forebrain morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7763844535 | 0.5842294138 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0845501842 |
| GSE13712_SHEAR | Up | 0.1610276561 |
| GSE13712_STATIC | Up | 0.1966286795 |
| GSE19018 | Down | -0.0452082204 |
| GSE19899_A1 | Down | -0.0480793583 |
| GSE19899_A2 | Down | -0.0202005514 |
| PubMed_21979375_A1 | Down | -0.3730420185 |
| PubMed_21979375_A2 | Down | -0.2557922277 |
| GSE35957 | Down | -0.0382443297 |
| GSE36640 | Down | -0.0915288709 |
| GSE54402 | Down | -0.1630637669 |
| GSE9593 | Up | 0.2399261045 |
| GSE43922 | Up | 0.0131644513 |
| GSE24585 | Up | 0.2694486453 |
| GSE37065 | Down | -0.0700335559 |
| GSE28863_A1 | Down | -0.0218163857 |
| GSE28863_A2 | Up | 0.0918222121 |
| GSE28863_A3 | Up | 0.2318458593 |
| GSE28863_A4 | Down | -0.1137698172 |
| GSE48662 | Down | -0.1316524117 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024293 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026712 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
